Regenerative potential of a combination of PRF and bioactive glass for the treatment of horizontal bone defects in stage II and stage III periodontitis: a split-mouth randomized controlled trial
Objective: The aim of the study was to evaluate the efficacy of calcium phosphosilicate bioactive glass in combination with Platelet Rich Fibrin (PRF) in the treatment of horizontal bone defects in stages II and III periodontitis. Materials and Methods: The randomized controlled trial included 51 sites of horizontal bone defects from 4 patients with stages II and III periodontitis. The three treatment groups were: Group A - open flap debridement (OFD) + bone graft +PRF gel; Group B - OFD+ bone graft+ PRF gel covered by PRF membrane; Group C - OFD alone. The clinical and radiographic...
Autores: Swathy Skumar, Nisha Krishnavilasom Jayakumari, Shruthi Sethuraman,
Objective: To assess levels of the biomarkers Plasminogen Activator Inhibitor-1 (PAI-1) and alpha 2-macroglobulin (2MG) in saliva and serum in healthy individuals and patients with and without type 2 diabetes mellitus (T2DM) before and after periodontal therapy. Materials and Methods: The 90 recruited subjects were divided into the three following groups: Group 1, with 30 healthy subjects; Group 2, with 30 systemically healthy subjects with stage II and III periodontitis; and Group 3, with...
Objective: The aim of the study was to evaluate the efficacy of calcium phosphosilicate bioactive glass in combination with Platelet Rich Fibrin (PRF) in the treatment of horizontal bone defects in stages II and III periodontitis. Materials and Methods: The randomized controlled trial included 51 sites of horizontal bone defects from 4 patients with stages II and III periodontitis. The three treatment groups were: Group A - open flap debridement (OFD) + bone graft +PRF gel; Group B - OFD+...
Objective: To assess the effectiveness of using aqueous and gaseous ozone in the gingival tissues of periodontitis patients. Materials and Methods: Two independent reviewers searched electronic databases (Lilacs, PubMed, Scopus, and Web of Science) using keywords specific to the topic. The variables extracted from each selected article included: type of study, sample size, population, periodontal parameters and age. The eligibility criteria included randomized clinical trials analyzing the...
Objective: To develop an application for patients, aimed at promoting disease awareness and making evidence-based recommendations to seek professional care or preventive strategies. Materials and Methods: Three expert periodontists identified parameters that, according to the evidence, could represent sociodemographic characteristics, signs, symptoms or medical conditions that can be important to alert the patient about periodontal health. Each parameter was transformed into a...
Introduction: The excessive gingival display (EGD), also known as gummy smile, is one of the most prevalent complaints from patients looking for a more esthetic smile. Among the treatment options for this problem are gingivectomy, with or without osteotomy, crown lengthening, botulinum toxin, lip repositioning surgery and orthognathic surgery — many times along with orthodontic treatment, depending on the cause of the problem. More recently, a polymethylmethacrylate-based (PMMA) cement has...
Objective: This clinical case report aims to demonstrate a successful treatment using an alternative technique for flapless immediate implant placement by letting the xenogeneic bone graft exposed to the oral environment. Case report: A flapless immediate implant placement into the fresh mandibular first molar socket was done. The alveolar gap was filled by deproteinized bovine bone mineral (DBBM) up to the level of the gingival margin, and the biomaterial was intentionally left exposed and...
