Clinical and Microbiological Investigation of the Effects of Probiotics Combined with Scaling and Root Planing in the Management of Chronic Periodontitis: A Randomized, Controlled Study
Aim: To assess the adjunctive effect of probiotics to scaling and root planing in the management of chronic periodontitis. Materials and methods: Thirty systemically healthy subjects in the age range of 20 - 55 years suffering from chronic generalized periodontitis were selected and randomly assigned to a control group of patients who received scaling and root planing (SRP) alone, or a test group of patients who received SRP supplemented with probiotic administration, i.e., Bifi lac lozenges. The following baseline clinical parameters were recorded at selected teeth: plaque index, gingival...
Autores: Preet Kanwal Dhaliwal, Vishakha Grover, Ranjan Malhotra, Anoop Kapoor,
Periodontitis is a chronic infl ammatory disease in the oral cavity caused by bacterial biofi lm attached to tooth surfaces. The periodontal pathogenic microorganisms trigger the disease process; however, the destruction of the periodontium is mostly caused by the host’s immune response to the bacterial insults. The main thrust of periodontal therapy has been centered traditionally on reducing the microbial load by mechanical and antimicrobial means. This approach has been reported to be...
The action of the sympathetic nervous system in the control of bone remodeling and immunoinfl ammatory responses is the basis of the hypothesis that its modulation can infl uence the progress of periodontal disease. The aim of this study was to analyze the effects of the blockade and of the activation of β-adrenergic receptors in periodontal disease in rats. Thirty-two rats were divided into four groups: 1) animals with induced periodontitis that received propranolol (a non-selective...
Background: The present clinical trial was designed to investigate the effectiveness of subgingivally delivered satranidazole (SZ) gel as an adjunct to scaling and root planing (SRP) in the treatment of smokers with chronic periodontitis. Methods: Sixty smoker subjects with probing depth (PD) ≥ 5 mm were selected. Thirty subjects each were randomly assigned to SRP + placebo and SRP + SZ. SZ or placebo (0.1 mL) was injected into the pocket using a syringe with a blunt cannula. The clinical...
Background: This preliminary study assesses the effects of initial periodontal treatment on salivary levels of 8-hydroxy-deoxyguanosine (8-OHdG) as a marker of oxidative stress in patients with chronic periodontitis (CP). Methods: At baseline, clinical parameters and saliva samples were obtained from 20 patients with CP and 10 patients with clinically healthy periodontium. Saliva samples were collected, and clinical periodontal measurements were repeated at 2, 4, and 8 weeks after initial...
Aim: To assess the adjunctive effect of probiotics to scaling and root planing in the management of chronic periodontitis. Materials and methods: Thirty systemically healthy subjects in the age range of 20 - 55 years suffering from chronic generalized periodontitis were selected and randomly assigned to a control group of patients who received scaling and root planing (SRP) alone, or a test group of patients who received SRP supplemented with probiotic administration, i.e., Bifi lac...
