Subgingival irrigation with phytotherapics adjunct to scaling and root planing on the treatment of experimental periodontal disease in rats
Aim: To evaluate subgingival irrigation with Matricaria recutita (MAT) and Plantago major (PLA) adjunct to scaling and root planing (SRP) on treatment of experimental periodontitis (EP). Design: EP was induced in 72 rats. After 7 days, animals were randomly distributed in groups: SRP – SRP and irrigation with saline; MAT - SRP and irrigation with MAT solution; and PLA - SRP and irrigation with PLA solution. Euthanasia was performed after 7, 15 and 30 days (n=8). It was evaluated colony-forming units (CFU), bone loss (BL), percentage of mature and immature collagen fibers, TRAP, RANKL and...
Autores: Luciana Prado Maia, Christine Men Martins, Marcela Lucio Caldeira, Taciane Menezes da Silveira, Carolina dos Santos Santinoni, Bibiana Dalsasso Velasques, Natália Marcumini Pola, Douglas Roberto Monteiro, Edilson Ervolino,
Aim: Patients’ decisions upon treatment are influenced by wide array of factors. The aim of the study was to investigate the reasons to prefer dental implants. Methods: Clinical evaluation forms were assessed retrospectively. The reasons were analyzed with Chi-square and t-tests. The independent variables with a p value less than 0.15 in univariate analysis were selected to include into the multiple logistic regression model as potential predictors. The final model in multiple logistic...
Aim: The objective of this study was to evaluate a machine learning model to identify periodontitis patients and their cultivable subgingival microbial features. Methods: We analyzed the composition of the subgingival microbiota in health, gingivitis and periodontitis using machine learning. A total of 1026 microbiological records comprising 73 healthy, 205 gingivitis and 748 periodontitis culture samples were analyzed for associated important features and patterns of clustering. Results:...
Several epidemiological studies have estimated periodontitis prevalence and distribution. In Brazil, national epidemiological surveys assessing the periodontal status of the population were conducted. Other regional studies have also used different methodologies. However, comparability of findings in different regions and in the country is yet to be addressed. This integrative review aimed to evaluate the epidemiology of periodontitis in Brazilian adults and summarize prevalence estimates of...
Aim: Age is not considered a prognostic determinant in surgical periodontal treatment planning even though it is a non-modifiable risk factor. Present study explores the effect of age on bone coupling mechanism at molecular level through Osteoprotegrin (OPG) and Receptor activator of nuclear factor kappa-B ligand (RANKL) following surgical pocket therapy in periodontitis. Methods: Forty-five generalized periodontitis patients were divided for surgical treatment into three groups based on age...
Aim: The present study was undertaken to evaluate the concentration of Periodontal Ligament Associated Protein-1 (PLAP-1) and Tumour Necrosis Factor – Alpha (TNF-α) in Gingival Crevicular Fluid (GCF) and serum in healthy, periodontitis (P) and P participants after the Non-Surgical Periodontal Therapy(NSPT). Materials and Methods: 26 participants with age (25-50yrs) was included in study. Based on clinical and radiological parameters these participants were divided as; group 1: healthy, group...
Aim: The purpose of this study was to perform a short-term evaluation of the effects of a probiotic, associated with the use of antibiotics as an adjuvant treatment of periodontitis in smokers. Materials and Methods: Thirty-four patients were randomly divided into: PRO group (n = 17), patients received a single session of scaling and root planing (SRP) associated with the systemic administration of Lactobacillus reuteri tablets; ANT+PRO group (n=17), patients received a single session of SRP...
Aim: To evaluate subgingival irrigation with Matricaria recutita (MAT) and Plantago major (PLA) adjunct to scaling and root planing (SRP) on treatment of experimental periodontitis (EP). Design: EP was induced in 72 rats. After 7 days, animals were randomly distributed in groups: SRP – SRP and irrigation with saline; MAT - SRP and irrigation with MAT solution; and PLA - SRP and irrigation with PLA solution. Euthanasia was performed after 7, 15 and 30 days (n=8). It was evaluated...
Aim: Vegetarian diets are known to reduce inflammation. We investigated the cross-sectional association of gingival fluid inflammatory cytokines with periodontal status in vegetarians and non-vegetarians. Methods: A total of 54 systemically healthy subjects were enrolled. Dietary intake was assessed by a food frequency questionnaire. A comprehensive periodontal examination was performed. Gingival fluid was collected, samples were assessed for interleukin 1β (IL-1β), interleukin 6 (IL-6),...
Aim: To systematically review the effects of platelet-rich fibrin applications on the palatal wounds of patients undergoing gingival graft harvest. Materials and Methods: An electronic search was performed (May 2020) in six databases: Cochrane Library, EMBASE, LILACS, PubMed, Scopus, and Web of Science. Pain and delayed bleeding were the outcomes assessed. The randomized clinical trials were submitted to risk analysis of bias (RoB 2.0 Cochrane Collaboration), and the Grading of...
