The Effect of Periodontal Diseases and Cognitive Deficit on Behavioral State, Oxidative Stress Parameters and Alveolar Bone Loss in Rats
Aims: To evaluate the effect of periodontal disease (PD) and cognitive deficit (CD) on behavioral state, oxidative stress parameters, and alveolar bone loss (ABL). Materials and Methods: Fifty male Wistar rats were randomly divided into five groups: control; scopolamine; periodontal disease (PD); PD+scopolamine evaluated by the Morris water maze behavioral test; PD+scopolamine assessed by the inhibitory avoidance behavioral test. PD and CD were, respectively, induced by ligature and scopolamine. Both the maxilla and mandible were morphometrically analyzed for ABL. For all animal groups,...
Autores: Cassiano Kuchenbecker Rösing, Marcelo Ekman Ribas, Francisco Wilker Mustafa Gomes Muniz, Tainara Steffens, Aline Gomes, Narlon Volpato, Narton Volpato, Gustavo Kociczeski, Luciano Pitoni, Emanuel Contini Bertol, Ana Cristina Roginski, Alexandre Umpierrez Amaral, Helissara Diefenthaeler,
Aims: To evaluate the effect of periodontal disease (PD) and cognitive deficit (CD) on behavioral state, oxidative stress parameters, and alveolar bone loss (ABL). Materials and Methods: Fifty male Wistar rats were randomly divided into five groups: control; scopolamine; periodontal disease (PD); PD+scopolamine evaluated by the Morris water maze behavioral test; PD+scopolamine assessed by the inhibitory avoidance behavioral test. PD and CD were, respectively, induced by ligature and...
Aims: The purpose of the present study was to compare the effect of a new mouth wash formulation consisting of chlorhexidine and chitosan on dental plaque and its reduction to that of chlorhexidine or chitosan alone. Materials and Methods: This study was a single-blind randomized clinical trial with a parallel group design of 3 months duration. Patients (20-40 years) who fulfilled the inclusion and exclusion criteria were assigned equally to group 1: chlorhexidine (0.2%), group 2: chitosan...
Aims: The purpose of this study was to evaluate the impact of fullfixed orthodontic appliances on the periodontium in adult patients. Methods: Seventeen periodontally and systemically healthy subjects were selected from the Periodontal Clinic of Guarulhos University, 7 males and 10 females (mean age: 38.3 ± 6.3 years). The patients undergoing orthodontic treatment were submitted a clinical examination, a cone beam computed tomography at baseline and after 12 months of treatment. Subgingival...
Aims: To report the periodontal condition of two siblings (ages 2 and 4) diagnosed with congenital Amegakaryocytic Purpura (AP), who underwent allogeneic hematopoietic stem cell transplant (HSCT) and developed graft-versus-host disease (GVHD) with oral manifestations. Methods: Clinical history was obtained through physical examination and medical records. Patients received clinical and microbiological assessment at 2 months post-HSCT, when they started to show signs and symptoms of GVHD and...
Aims: To systemically review the literature on the effect of hand and sonic/ultrasonic instruments used for the non-surgical treatment of periodontitis. Material and methods: Five databases were searched for randomized clinical trials that compared the results of periodontal treatment using hand and sonic/ultrasonic for nonsurgical periodontal treatment. Four meta-analyses were performed, using the calculated mean differences (MD) between baseline and 3-months or 6-months after periodontal...
Aims: Periodontal treatment is reported to be associated with an improved periodontal condition in diabetic patients. Therefore, a comprehensive review of meta-analyses was conducted to evaluate whether periodontal treatment can improve glycemic control in patients with type 2 diabetes. Materials and methods: The search on electronic databases included PubMed-Medline, Cochrane Library, Scopus, and LILACS databases. The methodological quality of the systematic reviews was evaluated using...
Aims: To investigate the use of ω-3 fatty acids and low-dose aspirin as adjuncts to periodontal debridement in a patient with periodontitis and metabolic syndrome. Methods: Periodontal and systemic parameters were assessed at baseline and 6 months. Gingival crevicular fluid was analyzed for interleukin (IL)-1β, IL-6 and interferon (IFN)-γ levels by multiplex ELISA at baseline, 3 and 6 months. Results: The treatment was effective in reducing probing depth, clinical attachment level,...
Aims: This study evaluated the mechanical properties of mandibular bone tissue retrieved from postmenopausal women under alendronate treatment. Methods: Twenty postmenopausal women were divided into two groups: healthy postmenopausal subjects (control group) and osteoporotic subjects treated with alendronate (alendronate group). Mandibular bone samples were retrieved with a trephine bur at the time of dental implant placement and fixed in 4% formalin. Samples were processed for hard tissue...
