Artigo: The effect of experimental periodontitis, experimental diabetes and their combination on the serum levels of adiponectin, leptin, IL-6, IL-18, MCP-1, RANTES and sICAM-1 in rats - JIAP v22n01 - DentalGO


The effect of experimental periodontitis, experimental diabetes and their combination on the serum levels of adiponectin, leptin, IL-6, IL-18, MCP-1, RANTES and sICAM-1 in rats

Background: The aim of this study was to assess ligature-induced periodontitis, streptozotocin- induced diabetes and their combination on serum levels of adiponectin, leptin, interleukin-6 (IL-6), interleukin-18 (IL-18), monocyte chemoattractant protein-1 (MCP- 1), regulated on activation, normal T cell expressed and secreted (RANTES) and soluble intercellular adhesion molecule-1 (sICAM-1). Materials and Methods: Forty-seven Wistar rats were studied: experimental periodontitis (13), experimental diabetes (10), experimental diabetes and experimental periodontitis (12) and health (12,...

Autores: Eudoxie Pepelassi, Ioanna Xynogala, Despina Perrea, George Agrogiannis, Alkistis Pantopoulou, Ioannis Vrotsos, 

Assessment of gingival phenotype through periodontal and crown characteristics: a cluster analysis
Assessment of gingival phenotype through periodontal and crown characteristics: a cluster analysis

Objective: To evaluate gingival phenotypes in 100 subjects (n = 100), with regard to maxillary central incisors and surrounding periodontium in an observational diagnostic study. Materials and Methods: Individuals were grouped based on: Probing depth (PD); keratinized mucosa (KM); Ratio Height/Width Crown (CH/CW), papilla area (PA), gingival thickness (GT) and Gingival Volume (GV). ANOVA and chi-square tests were performed with a significance level of 5%. Results: PD (p=0.860) and CH/CW...

Gingival crevicular fluid levels of prolactin hormone in periodontitis patients before and after treatment and in healthy controls
Gingival crevicular fluid levels of prolactin hormone in periodontitis patients before and after treatment and in healthy controls

Objective: Prolactin (PRL) acts as a hormone and as a cytokine and is linked to the pathogenesis of a variety of chronic inflammatory diseases. This study aimed to investigate a potential role for prolactin in the pathogenesis of periodontitis by assessing its local gingival crevicular levels before and after periodontal treatment, compared to controls. Materials and Methods: 40 participants were included and divided into 2 groups. Group 1; included 20 patients suffering from moderate to...

The effect of experimental periodontitis, experimental diabetes and their combination on the serum levels of adiponectin, leptin, IL-6, IL-18, MCP-1, RANTES and sICAM-1 in rats
The effect of experimental periodontitis, experimental diabetes and their combination on the serum levels of adiponectin, leptin, IL-6, IL-18, MCP-1, RANTES and sICAM-1 in rats

Background: The aim of this study was to assess ligature-induced periodontitis, streptozotocin- induced diabetes and their combination on serum levels of adiponectin, leptin, interleukin-6 (IL-6), interleukin-18 (IL-18), monocyte chemoattractant protein-1 (MCP- 1), regulated on activation, normal T cell expressed and secreted (RANTES) and soluble intercellular adhesion molecule-1 (sICAM-1). Materials and Methods: Forty-seven Wistar rats were studied: experimental periodontitis (13),...

The Novel Periosteal Flap Stretch Technique: A Predictable Method to Achieve and maintain Primary Closure in Augmentative Procedures
The Novel Periosteal Flap Stretch Technique: A Predictable Method to Achieve and maintain Primary Closure in Augmentative Procedures

Background: Correct soft tissue management and achieving tension-free primary closure are pre-requisites for the success of bone augmentation procedures. Several techniques have been developed to facilitate a passive soft tissue primary closure. However, the current techniques are highly invasive and require advanced surgical skills. Hence, the present case series report will describe a novel and simple flap management technique. Methods: The Periosteal Flap Stretch technique was utilized in...