Gingival Crevicular Fluid Release Profile Of Vascular Endothelial Cell Growth Factor And Platelet-derived Growth Factors – Bb Following Minimally Invasive Flap Reflection During Treatment Of Intrabony Defects: a Randomized Clinical Trial
Objectives: As a primary objective, we examined the gingival crevicular fluid (GCF) levels of the endogenously released platelet-derived growth factor (PDGF-BB) and vascular endothelial growth factor (VEGF) following the use of minimally invasive surgical flap reflection (MIS) and compared them with those in traditional open flap debridement (OFD). The secondary objective was to determine if any correlation exists between the expression of growth factors (GF), indicated by their levels, and associated clinical outcomes. Methods: Twenty-eight non-smoking individuals with severe chronic...
Autores: Ahmed S. Alzahrani,
This issue of the Journal of the International Academy of Periodontology marks the beginning of the twentieth year of publication. I am pleased and honored to have served as the Editor of the Journal since 1999, when then IAP President Thomas Van Dyke conceived of expanding the IAP mission through publication and dissemination of periodontal research in an IAP journal. Although during the first few years the Journal was faced with challenges, as all new journals are, we have subsequently...
It is with great excitement, but also trepidation, I embark on my role as Editor of the Journal of the International Academy of Periodontology. The Journal was established 19 years ago and has been under the careful stewardship of Dr Mark Patters, inaugural Editor. Mark (ably assisted by Andrea Patters, Associate Editor) has worked tirelessly to ensure the Journal presents a high-quality product of relevance to the international periodontal community. This has not been an easy task but Mark...
Objectives: As a primary objective, we examined the gingival crevicular fluid (GCF) levels of the endogenously released platelet-derived growth factor (PDGF-BB) and vascular endothelial growth factor (VEGF) following the use of minimally invasive surgical flap reflection (MIS) and compared them with those in traditional open flap debridement (OFD). The secondary objective was to determine if any correlation exists between the expression of growth factors (GF), indicated by their levels, and...
Objectives: The purpose of this study was to compare effects of smoking and smokeless forms of tobacco consumption (tobacco chewing) on periodontal disease parameters and response of these subjects to non-surgical periodontal therapy. Methods: One hundred sixty-eight patients with chronic periodontitis were screened for the study. Eighteen patients were excluded as they decided to quit the tobacco habit. One hundred fifty patients fulfilling the inclusion and exclusion criteria were grouped...
Objective: The composition and morphology of the internal and external surfaces of membranes are important for preventing migration of epithelial and connective cells, and allow the installation of osteogenic cells for bone growth. The objective of this study was to analyze the morphology and composition of three types of commercially available resorbable collagen membranes. Methods: Three types of collagen membranes, with different compositions and coming from different animals, were used:...
Objective: This study aimed to evaluate the effect of initial periodontal clinical parameters on the final outcome of the treatment of periodontal recessions by means of a coronally positioned flap (CPF). Materials and methods: The CPF technique was used in a total of 39 Miller Class I/ II gingival recessions of the upper canines and/or premolars. The clinical periodontal parameters evaluated were: probing depth, gingival recession height, gingival recession width, keratinized mucosa,...
Objective: Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is rarely reported as a complication after implants placement. In this article we report a combined treatment for a rare case of peri-implant BRONJ. Methods: A 71-year-old female patient presented for follow-up of a 4.3 x 13 mm implant placed on first upper-left premolar position 3 years prior. She was complaining of soreness of the area and bleeding when brushing. The patient had a history of breast cancer (removed 7 years...
The aim of this review is to give an update on various tooth extraction protocols for patients on bisphosphonate therapy. Presently there is an increasing prevalence of patients receiving bisphosphonate therapy. This review has included the pathogenesis of bisphosphonate-related osteonecrosis of the jaws (BRONJ) associated with tooth extraction, its effect on alveolar bone, epithelium, variations in healing time, angiogenesis, and the risk factors associated with BRONJ development, as well...
