Artigo: A Novel Formulation Effective in Killing Oral Biofilm Bacteria - JIAP v14n03 - DentalGO


A Novel Formulation Effective in Killing Oral Biofilm Bacteria

Artigo

Objective: To determine if a novel formulation is effective in killing oral biofilm streptococci in vitro and in vivo. Methods: Efficacy of 0.5% levulinic acid and 0.05% sodium dodecyl sulfate (SDS) in killing Streptococcus gordonii CH1, Streptococcus gordonii DL1, Streptococcus mitis NCTC10712, Streptococcus oralis KS32AR, Streptococcus mutans BM71, and Streptococcus mutans GS5 in their biofilm form was measured in vitro, using microtiter plates and subsequent counts on Mitis-Salivarius agar plates. The safety and efficacy in vivo were evaluated using a mouse model. Results: Our...

Autores: Sebastian G. Ciancio, Bing-Yan Wang, Jianming Hong, Tong Zhao, Michael P. Doyle, 

Enamel Matrix Derivative and Transforming Growth Factor-β1 in Class III Furcation Defects. A Histomorphometric Study in Dogs
Enamel Matrix Derivative and Transforming Growth Factor-β1 in Class III Furcation Defects. A Histomorphometric Study in Dogs

The objective of this study was to evaluate histomorphometrically, in dogs, the effect of enamel matrix derivative (EMD), with or without transforming growth factor-β1 (TGF- ), in a periodontal Class III furcation model. Class III furcation defects were created in P3 and P4 of six dogs. The defects were allowed to stabilize for 21 days. Four experimental conditions were established: G1: control (propylene glycol alginate); G2: EMD; G3: TGF- β1 and G4: EMD + TGF-β1. After 12 weeks, the...

Using Soft Tissue Graft to Prevent Mid-facial Mucosal Recession Following Immediate Implant Placement
Using Soft Tissue Graft to Prevent Mid-facial Mucosal Recession Following Immediate Implant Placement

Background: With advances in dental technology, the placement of immediate implants has progressively gained popularity. However, a common complication that surfaced was mid-facial mucosal recession, which impaired esthetic outcomes. The use of soft tissue grafts has thus been introduced to manage and prevent this undesirable result. To date, no guidelines have been put forward for clinicians to identify the indications for a soft tissue graft during immediate implant placement. Therefore,...

A Novel Formulation Effective in Killing Oral Biofilm Bacteria
A Novel Formulation Effective in Killing Oral Biofilm Bacteria

Objective: To determine if a novel formulation is effective in killing oral biofilm streptococci in vitro and in vivo. Methods: Efficacy of 0.5% levulinic acid and 0.05% sodium dodecyl sulfate (SDS) in killing Streptococcus gordonii CH1, Streptococcus gordonii DL1, Streptococcus mitis NCTC10712, Streptococcus oralis KS32AR, Streptococcus mutans BM71, and Streptococcus mutans GS5 in their biofilm form was measured in vitro, using microtiter plates and subsequent counts on Mitis-Salivarius...

One-year Re-entry Results of Guided Bone Regeneration around Immediately Placed Implants with Immediate or Conventional Loading: A Case Series
One-year Re-entry Results of Guided Bone Regeneration around Immediately Placed Implants with Immediate or Conventional Loading: A Case Series

Objective: The aim of this one-year, re-entry case series was to evaluate clinically the amount of bone regeneration following the placement of immediate implants in fresh extraction sockets where bone allograft has been used to treat horizontal gaps and buccalbone dehiscence defects in periodontally compromised patients. Methods: Sixteen patients consented to participate, each having one immediate implant with ≥ 3 mm buccal dehiscence bone defects and ≥ 2 mm horizontal defects between...