Clinical and Microbiological Effects of Adjunctive, Locally Delivered Chlorhexidine on Patients with Chronic Periodontitis
Artigo
Objective: The impact of a locally delivered chlorhexidine chip (Periochip®) on clinical and microbiological parameters of chronic periodontitis requires further documentation. The aim of the present study was to investigate the effects of the chip as an adjunct to mechanical treatment of chronic periodontitis. Methods: Fifty patients with chronic periodontitis were randomized into two groups. The test group (n = 25) received scaling and root planing and adjunctive Periochip® in four pockets. The control group (n = 25) received scaling and root planing only. Clinical indices (probing...
Autores: Sakellari Dimitra, Loannidis Loannis, Antoniadou Malama, Slini Theodora, Konstantinidis Antonis,
Objective: The impact of a locally delivered chlorhexidine chip (Periochip®) on clinical and microbiological parameters of chronic periodontitis requires further documentation. The aim of the present study was to investigate the effects of the chip as an adjunct to mechanical treatment of chronic periodontitis. Methods: Fifty patients with chronic periodontitis were randomized into two groups. The test group (n = 25) received scaling and root planing and adjunctive Periochip® in four...
Objective: The objective of this study was to investigate the association between the antimicrobial and clinical efficacy of minocycline hydrochloride microspheres when used adjunctively with scaling and root planing. Methods: 127 subjects with moderateto- advanced chronic periodontitis were randomly assigned to receive either minocycline microspheres plus scaling and root planing (n = 62) or scaling and root planing alone (n = 65). Deoxyribose nucleic acid analysis and clinical data were...
The sinus floor elevation technique with Summers’ osteotome is simpler and less invasive than access through the lateral wall of the sinus; however, it is susceptible to a higher level of sinusal membrane rupture. The objective of the present study was to display a modification of the osteotomy technique by connective tissue interposition in order to weaken the impact of sinus cortical fracture, and therefore prevent perforations in the sinusal membrane. A case is reported in which a...
Our understanding of the etiology and pathogenesis of periodontitis has dramatically improved over the last three decades. The primary etiological role of dental biofilm has been well established; a number of periodontal pathogens have been identified and characterized; and wide arrays of virulence factors and pathogenic mechanisms have been determined. It has also become clear that tissue damage in periodontitis is mostly the result of destructive host immune responses rather than a direct...
Host and bacterial proteases play a vital role in periodontitis. Inhibitors of these proteases are necessary for control of this disease. The purpose of this study was to evaluate the effect of lanthanides on proteins from Porphyromonas gingivalis, a major pathogen in periodontitis. Benzoyl-L-Arg-p-nitroanilide (BAPNA); H-Gly-Pro-pNA · HCl and gelatin were used to evaluate the activity of P. gingivalis proteins in the presence of lanthanides. Proteins extracted from cell surfaces and...
