Artigo: Porphyromonas gingivalis and Alzheimer’s disease: A narrative review - JIAP v27n01 - DentalGO


Porphyromonas gingivalis and Alzheimer’s disease: A narrative review

Artigo

Objective: The purpose of this review is to address the purported association of periodontitis and the microbial pathogen, Porphyromonas gingivalis (P. gingivalis), with Alzheimer’s disease (AD). Methods: A scoping search was conducted using terms related to biological plausibility, comorbid associations of periodontitis, P. gingivalis and AD. Ovid Medline and PubMed were used to obtain abstracts which, in turn, were used to select papers for further evaluation. Special attention was given to articles addressing confounders, risk factors, and causality. A total of 113 papers from the...

Autores: Dagmar E. Slot, Charles M. Cobb, Pin-Chuang Lai, Keerthana Satheesh, Simon R. MacNeill, 

ARTIGO ANTERIOR
Two Decades of International Periodontology from Heidelberg The Summerschool as a Model for Scientific Exchange, Clinical Excellence, and Global Networking
Two Decades of International Periodontology from Heidelberg The Summerschool as a Model for Scientific Exchange, Clinical Excellence, and Global Networking

The “International Summerschool for Clinical Periodontology and Implantology“ is a two-week international training program designed for dentists, particularly postgraduates and young faculty members providing both theoretical knowledge and hands-on skills in Periodontology and Implantology. The program integrates lectures, case discussions, interactive seminars, and practical courses. Since its introduction in 2004, it has been held biennially —with the exception of the covid...

Inflammation-mediated Polymicrobial Emergence and Dysbiotic Exacerbation (IMPEDE) hypothesis
Inflammation-mediated Polymicrobial Emergence and Dysbiotic Exacerbation (IMPEDE) hypothesis

Introduction: The nexus between periodontal inflammation and the polymicrobial biofilm in the gingival sulcus is critical to understanding the pathobiology of periodontitis. Both play a major role in the etiology and pathogenesis of periodontal diseases and each reinforces the other. However, this nexus is also at the center of a significant conundrum for Periodontology. For all mucosal polymicrobial biofilms, the most confounding issue is the paradoxical relationship between inflammation,...

Porphyromonas gingivalis and Alzheimer’s disease: A narrative review
Porphyromonas gingivalis and Alzheimer’s disease: A narrative review

Objective: The purpose of this review is to address the purported association of periodontitis and the microbial pathogen, Porphyromonas gingivalis (P. gingivalis), with Alzheimer’s disease (AD). Methods: A scoping search was conducted using terms related to biological plausibility, comorbid associations of periodontitis, P. gingivalis and AD. Ovid Medline and PubMed were used to obtain abstracts which, in turn, were used to select papers for further evaluation. Special attention was given...